These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effect of doxapram on neostigmine evoked antagonism of vecuronium neuromuscular block.
    Author: Orlowski M, Pollard BJ.
    Journal: Br J Anaesth; 1992 Apr; 68(4):418-9. PubMed ID: 1353679.
    Abstract:
    We have examined the effect of doxapram on neostigmine-evoked antagonism of vecuronium neuromuscular block in a double-blind study in anaesthetized patients. Neuromuscular transmission was measured with a Datex Relaxograph. The mean time to recovery of the first contraction of the train-of-four (T1) from 25% to 75% was significantly longer in the presence of doxapram (138 (SEM 21) s; n = 23) than in its absence (95 (13) s; n = 29) (P = 0.014). The recovery of the train-of-four ratio was prolonged also in the presence of doxapram, although this difference was not statistically significant.
    [Abstract] [Full Text] [Related] [New Search]