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  • Title: Somatostatin analogs in the treatment of acromegaly.
    Author: Lamberts SW, Reubi JC, Krenning EP.
    Journal: Endocrinol Metab Clin North Am; 1992 Sep; 21(3):737-52. PubMed ID: 1355729.
    Abstract:
    Medical therapy of acromegaly with the somatostatin analog octreotide is very successful. Both clinical symptomatology and hormonal hypersecretion by the growth hormone-secreting pituitary adenomas are controlled, and peripheral IGF-I levels also return to near normal levels. Tumor shrinkage is observed in most patients. Somatostatin analogs can be used after noncurative surgery and for a limited period after radiotherapy, and octreotide pretreatment might improve the outcome of surgery.
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