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  • Title: [An autopsy case of malignant rheumatoid arthritis (MRA) which was difficult to distinguish from polyarteritis nodosa (PN)].
    Author: Hidaka T, Suzuki K, Kawakami M, Hirose T, Harihgai M, Kitani A, Kawagoe M, Hara M, Nakamura H, Senoo A.
    Journal: Ryumachi; 1992 Aug; 32(4):318-24; discussion 324-6. PubMed ID: 1357757.
    Abstract:
    We encountered a patient who was diagnosed as rheumatoid arthritis (RA) at 15 years old and developed malignant RA (MRA) within one year. He suffered from mononeuritis multiplex and cutaneous infarction. Despite of treatment including steroid pulse therapy, neuritis progressed. Lung infiltration, pancreatitis and intestinal bleeding were accompanied. He died of disseminated intravascular coagulation on 153 days after admission. Autopsy revealed systemic rheumatoid vasculitis in coronary artery, pancreas, liver, small and large intestine, kidney and lung. These severe vasculitis occurred in young RA patient are rare case and it is important to consider the therapy and prognosis.
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