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  • Title: Study of the priming effect of interferon in L cells. I. The primed interferon response and the kinetics of development of priming.
    Author: Rosztóczy I.
    Journal: Acta Virol; 1976 Dec; 20(6):472-8. PubMed ID: 13642.
    Abstract:
    Interferon was detected one hour earlier, its production followed an enhanced pattern and became resistant to actinomycin D 30 minutes sooner in cultures primed by interferon pretreatment before stimulation by polyriboinosinic-polyribocytidylic acid than in unprimed cultures. The kinetics of development of the primed state was found to be a time and dose dependent phenomenon. The continuous presence of interferon during the pretreatment period was not required for the development of the primed state.
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