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  • Title: Alteration of root surface morphology by topical application of doxycycline hydrochloride on periodontally diseased human teeth.
    Author: Demirel K, Gwinnett AJ.
    Journal: Periodontal Clin Investig; 1992; 14(2):8-12. PubMed ID: 1364332.
    Abstract:
    The objective of this study was to describe the surface morphology of periodontally involved root cementum and its alteration following topically applied doxycycline hydrochloride to root-planed and non-planed samples. Root surfaces were treated with 100 mg/mL doxycycline hydrochloride solution for three minutes. A control group was treated with sterile saline. Observations made by scanning electron microscopy showed that treating the periodontally diseased cementum surfaces altered the surface topography significantly. Root planed, doxycycline-treated surfaces showed characteristics similar to those reported for citric acid conditioning. An important finding of the study was that the topical application of doxycycline hydrochloride also removed and/or altered the surface integument on non-planed root surfaces.
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