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  • Title: Inappropriate use of anti-asthmatic drugs in the Italian paediatric population.
    Author: Clavenna A, Rossi E, Berti A, Pedrazzi G, De Rosa M, Bonati M, ARNO Working Group.
    Journal: Eur J Clin Pharmacol; 2003 Oct; 59(7):565-9. PubMed ID: 13680035.
    Abstract:
    OBJECTIVE: To evaluate anti-asthmatic drug prescriptions in a large Italian paediatric population. METHODS: Prescriptions involving 417,559 children younger than 14 years old dispensed during 2000 by the retail pharmacies of 17 Italian local health units participating in the ARNO project were analysed. RESULTS: In the study, 92,890 children (22.2%) received at least one anti-asthmatic drug prescription. The prevalence of prescriptions was higher in children less than 1 year old, significantly decreased with increasing age, and was higher in boys than in girls. Of children treated with anti-asthmatic drugs, 71.5% received prescriptions of less than three boxes. Beclomethasone, salbutamol, flunisolide and fluticasone were the most prescribed drugs. Beclomethasone and flunisolide were prescribed mostly as nebulised suspension. CONCLUSIONS: The data suggest that anti-asthmatic drugs are often prescribed for diseases different from asthma and that many children are exposed to treatments for which there is no evidence of efficacy.
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