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  • Title: Bioassay-guided isolation and identification of antifungal compounds from ginger.
    Author: Ficker C, Smith ML, Akpagana K, Gbeassor M, Zhang J, Durst T, Assabgui R, Arnason JT.
    Journal: Phytother Res; 2003 Sep; 17(8):897-902. PubMed ID: 13680820.
    Abstract:
    A bioassay-guided isolation of antifungal compounds from an African land race of ginger, Zingiber officinale Roscoe, led to the identification of [6], [8] and [10]-gingerols and [6]-gingerdiol as the main antifungal principles. The compounds were active against 13 human pathogens at concentrations of <1 mg/mL. The gingerol content of the African land race was at least 3 x higher than that of typical commercial cultivars of ginger. Therefore, ginger extracts standardized on the basis of the identified compounds, could be considered as antifungal agents for practical therapy.
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