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  • Title: ["A life threatening event" in infants. Results of polysomnography and examination of a group of 122 infants].
    Author: Trowitzsch E, Meyer G, Schlüter B, Buschatz D, Andler W.
    Journal: Monatsschr Kinderheilkd; 1992 Apr; 140(4):233-6. PubMed ID: 1369824.
    Abstract:
    Survivors of an "apparent-life-threatening-event" subsequently more often die from sudden infant death syndrome than others. The aim of this study was to find out abnormal clinical symptoms and/or polysomnographic patterns in this group of patients. Between January 1989 and September 1990 122 infants (mean age 13.98 weeks) were examined after a life threatening event (mean age 9.3 weeks at the event). In total, 222 polysomnographic studies were performed. In 46 cases additional esophageal pH-metric measurements, and in 26 cases a Holter 24 hours monitoring were done. Seven infants were premature and had been ventilated, and 6 were siblings of sudden-infant-death-syndrome victims. Pulmonary problems were identified in 7 (6%), cardiac problems in 17 (14%), 18 (15%) had neurological problems, and 40 (33%) showed a gastroesophageal reflux. In 14 (11%) other diseases were found. Only 43 (35%) infants were without pathologic findings and were classified as having had an "idiopathic" event. The polysomnographic studies showed that obstructive apnea occurred significantly more often, the maximal duration of apnea was longer, and the number of sudden pO2 decreases was significantly higher than in a group of 188 normal infants. Thus, patients having had an "apparent-life-threatening-event" showed a broad spectrum of abnormal clinical symptoms and some respiration disturbances compared to a reference group of infants.
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