These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Protactin, a new antibiotic metabolite and a possible precursor of the actinomycins.
    Author: Hanada M, Sugawara K, Nishiyama Y, Kamei H, Hatori M, Konishi M.
    Journal: J Antibiot (Tokyo); 1992 Jan; 45(1):20-8. PubMed ID: 1372309.
    Abstract:
    Streptomyces cucumerosporus strain L703-4 (ATCC 53784) produces a new 4-methyl-3-hydroxyanthraniloylpentapeptide lactone for which we have proposed the name protactin, in addition to several actinomycin components. Protactin is rather resistant to air oxidation but it can be converted to a new actinomycin, actinomycin Zp by ferricyanide oxidation. Actinomycin Zp possesses in vitro antibacterial activity and in vivo antitumor activity against P-388 leukemia in mice.
    [Abstract] [Full Text] [Related] [New Search]