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  • Title: [Osteocalcin in diffuse toxic goiter].
    Author: Balabolkin MI, Khaiutina TL, Mkrtumian AM.
    Journal: Ross Med Zh; 1992; (1):13-5. PubMed ID: 1377070.
    Abstract:
    Bone metabolism was investigated in toxic goiter. The authors obtained evidence on high levels of osteocalcin which marks bone formation. The time of the thyroid function recovery during thyrostatic therapy and indices of phosphorus-calcium metabolism disagree indicating delayed normalization of the bone tissue metabolism. There is a correlation between the thyroid function, osteocalcin and oxyproline that indirectly confirms the action of thyroid hormones on the bone matrix; between osteocalcin levels and other indices of bone metabolism (serum alkaline phosphatase activity and oxyproline excretion).
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