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  • Title: Immunohistochemical study of the distribution of S-100 protein in pleomorphic adenomas of minor salivary glands.
    Author: Siar CH, Ng KH.
    Journal: J Nihon Univ Sch Dent; 1992 Jun; 34(2):96-105. PubMed ID: 1380072.
    Abstract:
    Twelve pleomorphic adenomas of minor salivary gland origin were examined for the distribution of S-100 protein, detected using the peroxidase-antiperoxidase (PAP) method. Strong S-100 protein immunoreactivity was noted in areas containing plasmacytoid cells, stellate and spindle cells against a myxochondroid or hyalinous stroma, and solid epithelial areas. Tubular and duct-like structures showed variable stainability. Stromal tissue and normal salivary glands were generally negative for S-100 protein. These findings were compared with those reported elsewhere.
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