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  • Title: The effect of piperazine on succinate production by Ascaris lumbricoides.
    Author: BUEDING E, SAZ HJ, FARROW GW.
    Journal: Br J Pharmacol Chemother; 1959 Dec; 14(4):497-500. PubMed ID: 13805677.
    Abstract:
    Piperazine reduced the production of succinate by Ascaris lumbricoides. This effect was reversible. There was a close parallelism between the concentrations of piperazine which paralysed the worm and those which inhibited the formation of succinate. Piperazine did not affect the incorporation of [2-(14)C]lactate into succinate by strips of Ascaris muscle. It was concluded that production of succinate supplies energy for the contraction of Ascaris muscle.
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