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  • Title: Dipole modelling of median nerve SEPs in normal subjects and patients with small subcortical infarcts.
    Author: Franssen H, Stegeman DF, Moleman J, Schoobaar RP.
    Journal: Electroencephalogr Clin Neurophysiol; 1992; 84(5):401-17. PubMed ID: 1382949.
    Abstract:
    Somatosensory evoked potentials (SEPs) to median nerve stimulation were analyzed by means of spatio-temporal dipole modelling in 6 normal subjects and 8 patients with small infarcts in the thalamo-cortical radiation or thalamus. The SEPs could be modelled by a tangentially and a radially oriented equivalent dipole in the region of the contralateral cortical hand area and an equivalent dipole located in the region of the brain-stem. In 3 patients with absence or reduction of amplitudes of cortically generated SEP components, the activity of both cortical dipoles was lost or reduced. In 2 patients the frontally recorded SEP component P20 was lost; in one of them the activity of mainly the tangential dipole was reduced.
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