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  • Title: Omentopexy for revascularization of free tracheal grafts in rats.
    Author: Hirata T, Yamazaki F, Fukuse T, Muro K, Yokomise H, Inui K, Takahashi Y, Hirai T, Hitomi S, Wada H.
    Journal: Thorac Cardiovasc Surg; 1992 Aug; 40(4):178-81. PubMed ID: 1384165.
    Abstract:
    In rats, we examined the effect of an omentum wrapping on the vascularization of the trachea and on regeneration of the mucosal epithelium in the very early stage after free tracheal grafting. Two pieces of trachea were obtained from each donor rat. One piece was transplanted into the peritoneal cavity of the recipient rat and wrapped with omentum. The other piece was transplanted subcutaneously into the abdominal wall, without omentopexy. Recipients were sacrificed at random on days 1, 2, 3, and 4 after operation (5 rats/day). The increase of blood vessels rose significantly earlier in the omentopexy tracheas than in those without omentopexy (p less than 0.01), with all the former showing a normal ciliated, columnar epithelium in the membranous region of the trachea on day 4, accompanied by excellent epithelial regeneration in the cartilaginous region. These results suggest that omentopexy causes revascularization to occur earlier and to be completed in a shorter time, and that it also promotes epithelial regeneration following free tracheal grafting.
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