These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Quinacrine-staining of neurones, and activity of purine nucleosides and nucleotides in marine and terrestrial invertebrates from several phyla.
    Author: Knight GE, Hoyle CH, Burnstock G.
    Journal: Comp Biochem Physiol C Comp Pharmacol Toxicol; 1992 Jun; 102(2):305-14. PubMed ID: 1385035.
    Abstract:
    1. The acridine derivative quinacrine was used to stain nerve fibres in internal organs of 17 species of marine and terrestrial invertebrates from seven different phyla. 2. The majority of preparations showed quinacrine-stained nerve fibres. There was a degree of variation, ranging from a dense network of nerve bundles to single fibres. Quinacrine-positive nerve cell bodies were also observed in some ganglia. 3. Pharmacological experiments were performed on a variety of isolated tissues from the different marine and terrestrial groups, in order to ascertain their sensitivity to adenine nucleosides and nucleotides. 4. Correlation is drawn between the ability of neurones within a tissue to bind quinacrine, and the ability of that tissue to respond to applied adenine nucleosides and nucleotides.
    [Abstract] [Full Text] [Related] [New Search]