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  • Title: Humoral immunity in Down's syndrome.
    Author: Bălăiţă C, Christodorescu D, Gherghina I, Iscrulescu C.
    Journal: Rom J Neurol Psychiatry; 1992; 30(1):55-61. PubMed ID: 1385974.
    Abstract:
    Carried out on 57 outpatients, the study was aimed to prove the existence of a disgammaglobulinemia in Down's syndrome. The event could not be attributed to hospitalization. Data indicate increased A and G immunoglobulinemias. In agreement with other authors Ig A level was found to be very high especially after the age of 5. Ig M titre in patients was reduced in comparison with that of the controls, regardless of the age group. Increase timing of IgA and Ig G concentrations tends to be more marked for the Ig A fraction. In patients ranging from 0 to 5 years the Ig A serum level is deficient.
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