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Title: A cDNA clone encoding the ADP/ATP translocase of Drosophila melanogaster shows a high degree of similarity with the mammalian ADP/ATP translocases. Author: Louvi A, Tsitilou SG. Journal: J Mol Evol; 1992 Jul; 35(1):44-50. PubMed ID: 1387687. Abstract: A complementary DNA clone encoding the ADP/ATP translocase in Drosophila melanogaster has been identified. It has been shown by sequence analysis to contain a single open reading frame that encodes a polypeptide 297 amino acids long. This polypeptide shows extensive similarities to the known eukaryotic translocase polypeptides, the similarity being greatest (up to 80% identity) to the mammalian ADP/ATP translocases. In situ hybridization to polytene chromosomes of D. melanogaster with the sequence characterized in this study showed localization at a single site on the X chromosome at 9E. DNA transfer hybridization experiments suggest that more than one gene coding for the ADP/ATP translocase is present in the D. melanogaster genome.[Abstract] [Full Text] [Related] [New Search]