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  • Title: Effects of chronia excess salt ingestion. Evidence that genetic factors play an important role in susceptibility to experimental hypertension.
    Author: DAHL LK, HEINE M, TASSINARI L.
    Journal: J Exp Med; 1962 Jun 01; 115(6):1173-90. PubMed ID: 13883089.
    Abstract:
    Using the genetic technique of selective inbreeding, it has been possible to quickly develop two statistically separable populations from one unselected strain of Sprague-Dawley rats. One of these is very sensitive, the other very resistant, to the development of experimental hypertension from a high salt diet. It was suggested that similar genetic factors operate in man.
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