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  • Title: Effects of cyclopiazonic acid, an inhibitor of the Ca++ ATPase of sarcoplasmic reticulum, on Ca++ transport, contraction and relaxation in cardiac muscle.
    Author: Lahouratate P, Quiniou MJ, Léoty C.
    Journal: Adv Exp Med Biol; 1992; 311():343-5. PubMed ID: 1388315.
    Abstract:
    Cyclopiazonic acid is a potent inhibitor of cardiac sarcoplasmic reticulum Ca++ ATPase. It scarely affects inotropism but significantly impairs lusitropism suggesting a greater role for cardiac sarcoplasmic reticulum in the control of cardiac relaxation than in the control of cardiac contraction.
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