These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effects of bacterial endotoxin on rabbit platelets. I. Platelet aggregation and release of platelet factors in vitro.
    Author: DES PREZ RM, HOROWITZ HI, HOOK EW.
    Journal: J Exp Med; 1961 Dec 01; 114(6):857-74. PubMed ID: 13885652.
    Abstract:
    Incubation of platelet-rich rabbit plasma with E. coli endotoxin at 37 degrees C results in platelet aggregation and transfer of platelet 5-hydroxytryptamine to plasma. Release of 5HT is influenced by dose of endotoxin, type of anticoagulant, and temperature of incubation. A heat-labile plasma factor is necessary for the platelet-endotoxin interaction. Additional studies have shown that incubation of endotoxin with platelet-rich rabbit plasma also results in release of platelet phospholipid and bactericidins active against B. subtilis.
    [Abstract] [Full Text] [Related] [New Search]