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  • Title: [AIDS in children. Experience at the National Institute of Pediatrics].
    Author: Desinor-Mompoint OI, González-Saldaña N, Palacios-Saucedo G, Gutiérrez-Ortiz B, de León-Bojorge B, Vázquez-Rivera M.
    Journal: Bol Med Hosp Infant Mex; 1992 Sep; 49(9):566-72. PubMed ID: 1388780.
    Abstract:
    We describe retrospectively the experience with 44 cases of AIDS from January 1987 to October 1991 at the Instituto Nacional de Pediatria, a tertiary care children hospital in Mexico City. All patients with 2 ELISA and a positive Western Blot test were included. Thirty three patients were infected perinatally (75%) and 11 through blood transfusion (25%). Fourty one patients belonged to the P2 classification of the Centers for Disease Control. Chronic diarrhea (77%), lymphadenopathy (75%), hepatomegaly/splenomegaly (70%) and oral candidiasis (61%) were the most common clinical findings. Twenty patients died (45.4%). No statistical relation were found between survival rate and the way of transmission and age at onset. Autopsy was performed in 14 patients and revealed a sharp decrease of lymphoid tissue at all levels with severe thymic atrophy.
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