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  • Title: [Nephrotic syndrome associated with AIDS in children].
    Author: Muñoz-Arizpe R, Romero-Navarro B, Gómez-Chico R, Velásquez-Jones L, Samudio-Domínguez G, Ramón-García G, Valencia-Mayoral P.
    Journal: Bol Med Hosp Infant Mex; 1992 Sep; 49(9):600-4. PubMed ID: 1388785.
    Abstract:
    Several renal and renal-related disturbances have been described in patients with AIDS (acquired immune deficiency syndrome), in adults and children as well. These are mainly electrolyte and acid-base imbalance, acute renal failure and nephrotic syndrome. The latter is usually steroid non-responder. The renal histopathological lesions described more commonly are minimal change, mesangial hyperplasia and focal segmental glomerulosclerosis. Herein, we describe a 5 year-old with AIDS, that developed nephrotic syndrome, characterized by edema, ascites, hypoalbuminemia and massive proteinuria. A percutaneous renal biopsy showed mesangial proliferation. She did not respond to a 6 week treatment with prednisone. She died with sepsis after several viral and bacterial infections.
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