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  • Title: Osmotic swelling and membrane conductances in A6 cells.
    Author: Granitzer M, Bakos P, Nagel W, Crabbé J.
    Journal: Biochim Biophys Acta; 1992 Oct 05; 1110(2):239-42. PubMed ID: 1390853.
    Abstract:
    Hyposmotic basolateral perturbations (-30 mosmol/kg) in cultured renal layers (A6) increased basolateral membrane conductance more than 2-fold within 10 min; the increase was partly due to upregulation of K+ conductance, but other conductive pathways were also activated. The raise in apical membrane amiloride-sensitive Na+ conductance was less pronounced; it appears to be due to secondary effects.
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