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  • Title: Lung mechanics (FRC and static pressure-volume diagram) after endotracheal surfactant instillation: preliminary observations.
    Author: Svenningsen NW, Björklund L, Vilstrup C, Werner O.
    Journal: Biol Neonate; 1992; 61 Suppl 1():44-7. PubMed ID: 1391265.
    Abstract:
    Preliminary measurements of functional residual capacity (FRC) with the sulphurhexafluoride technique and static pressure volume diagrams were performed in newborn infants with respiratory distress syndrome receiving endotracheal instillation of natural porcine surfactant (Curosurf, 100 or 200 mg/kg). Within the first hour after surfactant treatment there was an increase in FRC and distensibility of the lungs persisting for 24-48 h.
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