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  • Title: [Natural history of Huntington's chorea].
    Author: Roccatagliata G, Albano C.
    Journal: Riv Neurol; 1976; 46(4):297-332. PubMed ID: 139673.
    Abstract:
    The scope of the work is to list and analyse, after a historical introduction on the subject, the principle clinical characteristics of "Huntington's Disease". The epidemiological aspects, those clinical-semeiotical, the course of the disease and the type of after affects of Huntington's Diseases are examined. The more significant details of the natural history of the chorea maior, as emerge from the literature, are compared with those that result from the study of the thirty cases of this chronic disease. In particular the following are analysed, the genetic aspects, the character of the psycho-organic deterioration of the chronic chorea, the psychiatric component and various clinical-semeiotical formalities, how the disease begins, its course, its duration, etc. The authors conclude pointing out the particular character of the dementia of Huntington's Disease, (of the pre-frontal type), the strong psychopathological incidence and the particular formalities of hereditary transmission of the mendelian type of this singular disease.
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