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  • Title: PROTECTION OF RENAL FUNCTION DURING SURGERY OF THE ABDOMINAL AORTA.
    Author: BAIRD RJ, FIROR WB, BARR HW.
    Journal: Can Med Assoc J; 1963 Oct 05; 89(14):705-8. PubMed ID: 14065073.
    Abstract:
    The operative and postoperative urinary output of 55 patients who underwent surgery for ruptured abdominal aortic aneurysms, unruptured abdominal aortic aneurysms, and aorto-iliac occlusive disease was recorded. There were five cases of postoperative anuria among 28 patients who received no free fluid in the immediate preoperative period. No case of anuria occurred in 27 patients who received either: (1) a water load of 5% dextrose in water or (2) 20% mannitol solution. The patients who received mannitol had a markedly greater operative and postoperative urinary output.Intravenous infusion of mannitol is recommended during the preoperative and operative period in patients with ruptured aneurysms of the abdominal aorta.
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