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  • Title: POLYRIBOSOMES: SIZE IN NORMAL AND POLIO- INFECTED HELA CELLS.
    Author: RICH A, PENMAN S, BECKER Y, DARNELL J, HALL C.
    Journal: Science; 1963 Dec 27; 142(3600):1658-63. PubMed ID: 14075695.
    Abstract:
    HeLa cells normally contain a distribution of polysome sizes, and the largest polysomes contain over 40 ribosomes. After infection with polio virus and actinomycin-D treatment, a new class of polio-induced polysomes are found, some of which contain up to 60 ribosomes. Examinaton of these polysomes suggests a mechanism for protein synthesis with this polycistronic RNA.
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