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Title: ELECTRON MICROSCOPIC AND BIOCHEMICAL STUDIES OF PYRUVATE DEHYDROGENASE COMPLEX OF ESCHERICHIA COLI. Author: REED LJ, FERNANDEZ-MORAN H, KOIKE M, WILLMS CR. Journal: Science; 1964 Aug 28; 145(3635):930-2. PubMed ID: 14163814. Abstract: Examination with the electron microscope of the pyruvate dehydrogenase complex and its component enzymes from Escherichia coli indicates that the complex has a polyhedral structure with a diameter of about 300 to 350 angstroms and a height of 200 to 250 angstroms. The reconstituted complex closely resembles the native complex in appearance. A tentative model of this multienzyme complex is proposed on the basis of the correlated biochemical and electron-microscopic data[Abstract] [Full Text] [Related] [New Search]