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  • Title: GAMMA GLOBULIN: UNMASKING OF HIDDEN ANTIGENIC SITES ON LIGHT CHAINS.
    Author: NACHMAN RL, ENGLE RL.
    Journal: Science; 1964 Jul 10; 145(3628):167-70. PubMed ID: 14171555.
    Abstract:
    Normal light (L) chains cleaved from normal pooled human gamma globulin contain immunologic determinants not overtly present in the native unreduced molecule. These hidden determinants are shared with Bence Jones proteins. Similarly, one of two Bence Jones proteins contained immunologic determinants which were not overtly present on the autologous serum myeloma protein.
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