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Title: POEMS syndrome--a case report. Author: Kim JW, Lee SK, Ha KM, Kim KH, Joh GY, Kim HJ, Yang SO, Hong SH. Journal: J Korean Med Sci; 1992 Mar; 7(1):79-84. PubMed ID: 1418769. Abstract: POEMS syndrome is a multisystem disorder associated with polyneuropathy, organomegaly, endocrinopathy, a monoclonal protein (M-protein), and skin changes. The authors describe a patient with POEMS syndrome who had osteosclerotic myeloma confirmed by open bone biopsy. Magnetic resonance imaging (MRI) showed discrete lesions of low signal intensity in both T1 and T2-weighted images. This patient is now being successfully treated with melphalan and prednisone with much improvement in skin thickening and sensory change in the lower extremities.[Abstract] [Full Text] [Related] [New Search]