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  • Title: Secretion of bovine alpha-lactalbumin into the milk of transgenic rats.
    Author: Hochi S, Ninomiya T, Waga-Homma M, Sagara J, Yuki A.
    Journal: Mol Reprod Dev; 1992 Oct; 33(2):160-4. PubMed ID: 1418984.
    Abstract:
    Bovine alpha-lactalbumin (b alpha LA) gene prepared by polymerase chain reaction was introduced into rat genomes by microinjection. Out of 17 transgenic rat lines, 11 secreted b alpha LA into their milk at concentrations higher than 0.2 micrograms/ml. Of these, three lines secreted b alpha LA at concentrations higher than those in bovine milk. The highest concentration of b alpha LA secreted into rat milk was 2,400 micrograms/ml.
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