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  • Title: [Role of T-lymphocytes in the mechanisms of hemopoiesis-inducing microenvironment activation in inflammation].
    Author: Dygaĭ AM, Klimenko NA, Gumilevskiĭ BIu, Gol'dberg ED.
    Journal: Biull Eksp Biol Med; 1992 May; 113(5):514-6. PubMed ID: 1421275.
    Abstract:
    On the model of acute infectious peritonitis in mice, the inflammation was shown to accompany pronounced activation of bone marrow haemopoiesis. The increased number of committed precursor cells of erythro- and granulomonocytopoiesis, morphologically differentiated elements and enhancing colony-stimulating and erythropoietic activities of GIM cells origin were shown as well. Thy 1.2+ cells, migrating to bone marrow, were shown to play an important role in hemopoiesis stimulation inflammation. These stimulate the processes of myeloid precursor proliferation directly (by means of lymphokines) and in cooperation with monocytes-macrophages of GIM.
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