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  • Title: Mutagenic activity of copper(II) chromate and dichromate complexes with polypyridines.
    Author: Szyba K, Golonka MC, Gasiorowski K, Urban J.
    Journal: Biometals; 1992; 5(3):157-61. PubMed ID: 1421966.
    Abstract:
    Copper(II) chromate and dichromate complexes with 2,2'-bipyridyl and 1,10-phenathroline were tested for their mutagenic activity in the standard Ames test. All of six tested complexes exhibited markedly lower mutagenic activity than the reference compounds--potassium dichromate and sodium chromate. The blockage of Cr(VI) reduction capability in the presence of the complex Cu2+ ion and the competition between copper and chromium ions in the interaction with cellular components are discussed in the light of the results of our previous chemical study.
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