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  • Title: Acromegaly and its treatment in the McCune-Albright syndrome.
    Author: Premawardhana LD, Vora JP, Mills R, Scanlon MF.
    Journal: Clin Endocrinol (Oxf); 1992 Jun; 36(6):605-8. PubMed ID: 1424186.
    Abstract:
    The McCune-Albright syndrome, comprising polyostotic fibrous dysplasia, cutaneous pigmentation and endocrine hyperfunction, is occasionally complicated by acromegaly due to a pituitary adenoma. We report a patient with the McCune-Albright syndrome and acromegaly, who developed secondary hypothyroidism and hypoadrenalism, in whom surgical removal of the pituitary tumour was technically difficult. A combination of a long-acting somatostatin analogue ('Sandostatin') and external irradiation were therefore used as treatment.
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