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  • Title: [Effect of an extract of mouse Ehrlich ascitic tumor cells on mitotic activity and DNA synthesis in that tumor].
    Author: Antokhin AI, Barysheva VP, Romanov IuA, Rybakov VP.
    Journal: Biull Eksp Biol Med; 1977 Jul; 84(7):86-8. PubMed ID: 142534.
    Abstract:
    The extract of Ehrlich's ascitis tumour cells depressed specifically the proliferative activity of this tumour cells. This was expressed in a marked reduction in the number of dividing and DNA-synthesizing cells after the extract injection. The mitotic index fell considerably as soon as 2 hours after the injection, reached the minimum in 4 to 5 hours and was restored to the control level in 9 to 12 hours. The radioactive index appeared to be evenly decreased in the course of 18 hours of the experiment.
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