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  • Title: [Phentolamine and dibenamine action on the carotid reflexes induced by lobeline].
    Author: Moniz de Bettencourt J, Carvalho JS, Pinto BG, Pimentao JB.
    Journal: C R Seances Soc Biol Fil; 1977; 171(2):329-32. PubMed ID: 142550.
    Abstract:
    On the carotid reflexogenic zone lobeline provoques : 1) a increase of amplitude and rate of respiratory movements with bradycardia and hypotension ; 2) a secondary decrease of amplitude and rate of breathing with tachycardia. Acting on the reflexogenic zone, phentolamine and dibenamine provoque a transitory weakening or disappearance of these reflexes. These effects are induced by a local action, because they are not observed by intravenous injection of the drugs and the lobeline reflexes starting from the carotid sinus of the other side are not affected.
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