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  • Title: Diagnostic and prognostic value of bromide partition test in tuberculous meningitis.
    Author: Bayas SL, Chandak VL, Ghate SV.
    Journal: Indian Pediatr; 1992 Jul; 29(7):851-5. PubMed ID: 1428133.
    Abstract:
    Bromide partition ratio was determined in 32 cases of tuberculous meningitis, 6 pyogenic meningitis, 8 viral meningitis and 9 cases of febrile convulsions. Bromide partition ratio below the critical value of 1.6 was present in 30 out of 32 tuberculous meningitis patients (93.74%) whereas all the control children had a ratio above 1.6. Two children who were on regular chemotherapy showed progressively rising ratio. It is concluded that in doubtful cases with inconclusive CSF picture, a low bromide partition ratio is a strong reason for starting antituberculous treatment without any delay. A very low ratio also suggests poor prognosis.
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