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  • Title: A MATHEMATICAL MODEL OF THE HUMAN RESPIRATORY CONTROL SYSTEM.
    Author: MILHORN HT, BENTON R, ROSS R, GUYTON AC.
    Journal: Biophys J; 1965 Jan; 5(1):27-46. PubMed ID: 14284328.
    Abstract:
    The respiratory system exhibits the properties of a control system of the regulator type. Equations describing this biological control system have been derived. Transient and steady-state solutions for various CO(2) and O(2) step input disturbances were obtained utilizing a digital computer and are compared with experimental results. The effectiveness of the respiratory system as a regulator is investigated. Further extensions of the model are suggested.
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