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  • Title: Guided tissue regeneration in interproximal defects in the monkey.
    Author: Caton J, Wagener C, Polson A, Nyman S, Frantz B, Bouwsma O, Blieden T.
    Journal: Int J Periodontics Restorative Dent; 1992; 12(4):266-77. PubMed ID: 1428607.
    Abstract:
    The potential for guided tissue regeneration was evaluated in one-walled interproximal sites in Macaca fascicularis. Histologic differences were evaluated at 1 and 3 months. Within the experimental (barrier) group, 100% of the root surfaces with potential for regeneration were covered with new cementum, whereas the control specimens had 20% or less new cementum. The amount of regeneration was determined by the position of the barrier membrane; the more coronal the barrier, the greater the regeneration. Observations indicated that the optimal time for barrier removal is between 1 and 3 months.
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