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  • Title: Penicillin-induced immune-mediated hemolytic anemia in a horse.
    Author: McConnico RS, Roberts MC, Tompkins M.
    Journal: J Am Vet Med Assoc; 1992 Nov 01; 201(9):1402-3. PubMed ID: 1429188.
    Abstract:
    A 5-year-old female American Quarter Horse was determined to have immune-mediated hemolytic anemia after detection of a positive response to a direct Coombs' test. Penicillin-induced immune-mediated hemolytic anemia was confirmed via a direct antiglobulin test, using penicillin-coated RBC. The horse was clinically improved and the anemia resolved in response to supportive care and discontinuation of penicillin treatment. Penicillin should be considered a possible cause of immune-mediated hemolytic anemia in horses.
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