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  • Title: Lactimidomycin, a new glutarimide group antibiotic. Production, isolation, structure and biological activity.
    Author: Sugawara K, Nishiyama Y, Toda S, Komiyama N, Hatori M, Moriyama T, Sawada Y, Kamei H, Konishi M, Oki T.
    Journal: J Antibiot (Tokyo); 1992 Sep; 45(9):1433-41. PubMed ID: 1429229.
    Abstract:
    Streptomyces amphibiosporus R310-104 (ATCC 53964) produced a novel antibiotic lactimidomycin which showed inhibitory activity against fungi and prolonged the survival time of mice transplanted with experimental tumors. Structural studies clarified that lactimidomycin is a new glutarimide antibiotic having a unique unsaturated 12-membered lactone ring.
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