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  • Title: Is cord blood erythropoietin a marker of intrapartum hypoxia?
    Author: Halevi A, Dollberg S, Manor D, Nussinovich R, Kaempfer R, Gale R.
    Journal: J Perinatol; 1992 Sep; 12(3):215-9. PubMed ID: 1432275.
    Abstract:
    A sensitive assay was used to compare the biological activity of cord serum erythropoietin in two groups of infants born with or without labor-induced hypoxia. The mean cord serum erythropoietin activity in 161 infants delivered after vaginal labor was 116 +/- 36 mU/mL, and was indistinguishable from that observed in 23 infants delivered by preplanned, elective cesarean section, 114 +/- 12 mU/mL (P = .75). The bioassay measured effective erythropoietin activity, including the contribution of potentiators in serum. These results indicate that duration and intensity of labor are insufficient to cause a significant increase in effective erythropoietin activity.
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