These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: ABNORMAL IMMUNE MECHANISM IN ALLOGENEIC RADIATION CHIMERAS.
    Author: GENGOZIAN N, RABETTE B, CONGDON CC.
    Journal: Science; 1965 Aug 06; 149(3684):645-7. PubMed ID: 14331188.
    Abstract:
    Mice were subjected to x-rays (950 roentgens) and injected with isogeneic (isologous) or allogeneic (homnologous) bone marrow. Six to 8 months later these chimeras were injected with Salmonella typhi flagellar antigen, and the formation of antibodies resistant and sensitive to destruction by treatment in vitro with 2-mercaptoethanol was determined. The allogeneic chimeras showed almost normal amounts of serumn antibody after a third injection of antigen but a relative defect in their ability to synthesize antibody resistant to 2-mercaptoethanol. Apparently control of antibody formation becomes abnormal in the presence of the immunologic tolerance existing between the host and the foreign hematopoietic graft.
    [Abstract] [Full Text] [Related] [New Search]