These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: ACE inhibition in diabetic patients: effect on pressor responsiveness to noradrenaline.
    Author: Strocchi E, Malini PL, Ciavarella A, Valtancoli G, Ricci C, Mustacchio A, Vannini P, Ambrosioni E.
    Journal: J Hum Hypertens; 1992 Aug; 6(4):317-9. PubMed ID: 1433167.
    Abstract:
    The pressor responsiveness to noradrenaline was assessed before and after four weeks of treatment with enalapril (20 mg/day) in eight mild-to-moderate essential hypertensives, in eight normotensive type II diabetics and in eight mild-to-moderate hypertensive type II diabetic patients. The ACE inhibitor interfered to the same extent with the renin-angiotensin system and did not alter noradrenaline kinetics in the three groups of patients, but significantly reduced the arterial responsiveness only in non-diabetic subjects. It is suggested that factors, such as an exaggerated sodium retention, might determine the lack of effect of enalapril in diabetic patients.
    [Abstract] [Full Text] [Related] [New Search]