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  • Title: [Changes, induced by certain flavonoids, of the hypotensive effects of arachidonic acid].
    Author: Damas J, Mousty JC, Lecomte J.
    Journal: C R Seances Soc Biol Fil; 1977; 171(1):257-60. PubMed ID: 143326.
    Abstract:
    In the rat, silybine and Z 12007, a derivative of rutoside, increase the vasodepressive activities of arachidonic acid, a prostaglandin precursor. They reduce the activity of PGE2. Quercetine also increases the hypotensive action of arachidonic acid. These three flavonoids are supposed to increase the prostaglandin biosynthesis.
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