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  • Title: Effect of inhalation anaesthetics on total respiratory resistance in conscious ponies.
    Author: Hall LW, Young SS.
    Journal: J Vet Pharmacol Ther; 1992 Jun; 15(2):174-9. PubMed ID: 1433479.
    Abstract:
    Total respiratory resistance was measured rapidly and non-invasively in 6 conscious ponies before and after they inhaled approximately 25% of the minimal anaesthetic concentration (0.25 MAC) of either enflurane, halothane, or isoflurane, over a 10 min period. The forced random noise (FRN) method was used to measure the impedance over the frequency range of 5 to 40 Hz and its real part, the resistance, was extracted from these impedance measurements. At the concentrations used, halothane appeared to have no effect on the total respiratory resistance; enflurane and isoflurane seemed to increase it but the changes were not statistically significant.
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