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  • Title: PHYSIOCHEMICAL AND BIOLOGICAL PROPERTIES OF GLYCOPROTEINS ISOLATED FROM THE PLASMA OF DIFFERENT SPECIES OF ANIMALS.
    Author: ANANTHASAMY TS, NATARAJAN S, CAMA HR.
    Journal: Biochem J; 1965 Jul; 96(1):281-8. PubMed ID: 14343145.
    Abstract:
    1. Glycoproteins were isolated from the plasma of sheep, goat, cow, buffalo and monkey. They were homogeneous by electrophoresis; on ultracentrifugation, a faster-sedimenting fraction, to an extent of 5-8% only, was observed in each case. 2. Similar physical properties were exhibited by these glycoproteins and they each have a molecular weight of about 105000. 3. In chemical composition, differences have been observed and the glycoproteins can be classified into three groups: (a) sheep and goat glycoproteins; (b) cow and buffalo glycoproteins; (c) monkey glycoprotein. Glucose, galactosamine and N-terminal amino acid were absent from these proteins. 4. These glycoproteins were trypsin inhibitors and prolonged the clotting time of plasma.
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