These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Leukemic cell kill in autologous bone marrow transplantation: in vivo or in vitro?
    Author: Hagenbeek A.
    Journal: Leukemia; 1992 Nov; 6 Suppl 4():85-7. PubMed ID: 1434842.
    Abstract:
    Both the contribution of high dose chemo-radiotherapy ("conditioning treatment") prior to autologous bone marrow transplantation (ABMT) and "purging" of autologous marrow grafts to the prevention of leukemia relapse are being addressed in the present communication. Based on both preclinical and clinical studies, it is concluded that cures achieved after ABMT are mainly due to effective eradication of residual leukemic cells in the host. The chance that leukemia will relapse is due to leukemic cells reinfused with the graft is estimated to be less than 10%.
    [Abstract] [Full Text] [Related] [New Search]