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  • Title: Temporomandibular joint: surgically created disk displacement causes arthrosis in the rabbit.
    Author: Macher DJ, Westesson PL, Brooks SL, Hicks DG, Tallents RH.
    Journal: Oral Surg Oral Med Oral Pathol; 1992 Jun; 73(6):645-9. PubMed ID: 1437028.
    Abstract:
    To document a causal relationship between temporomandibular joint disk displacement and arthrosis, the disk was surgically displaced in one temporomandibular joint in each of three rabbits. The rabbits were sacrificed after 4 weeks and the mandibular condyles were studied radiographically and histologically. All three joints that underwent disk displacement had radiographic and histologic evidence of arthrosis, which included erosion of the bone, irregularity and fissure formation of the articular soft tissue cover, disruption of the subchondral layer of cartilage cells, and chondrocyte proliferation. No radiographic or histologic changes occurred in the joints that were untouched. The results suggest that surgically created disk displacement can cause arthrosis in the temporomandibular joint of the rabbit.
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