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  • Title: Isoenzyme characterization of Leishmania braziliensis braziliensis isolates obtained from Bolivian and Peruvian patients.
    Author: Revollo S, Dimier-David L, David C, Lyevre P, Camacho C, Dedet JP.
    Journal: Trans R Soc Trop Med Hyg; 1992; 86(4):388-91. PubMed ID: 1440812.
    Abstract:
    Thirty-four Leishmania isolates obtained from Bolivian and Peruvian patients infected with mucocutaneous leishmaniasis were characterized by isoenzyme electrophoresis using 10 enzymatic markers; all belonged to the subspecies L.b. braziliensis. Three isolates showed marked variation compared with the reference strain with respect to 5 or 6 enzymes. These variant isolates originated from patients with forms of the disease which were unresponsive to treatment.
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